A foundation model-enhanced CT radiomics signature for the noninvasive assessment of tertiary lymphoid structures and prediction of therapy benefit in gastric cancer

Gastric cancer is a highly heterogeneous tumor type whose treatment responses substantially vary across patients. In recent years, biomarkers have shown promise in guiding individualized treatment regimens for gastric cancer, particularly for targeted therapy and immunotherapy[1][1]. Existing

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Publication Details

Journal
Cancer Biology and Medicine
Published
2026-04-16
DOI
https://doi.org/10.20892/j.issn.2095-3941.2026.0076
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
Field-Weighted Citation Impact
0.00
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article

A foundation model-enhanced CT radiomics signature for the noninvasive assessment of tertiary lymphoid structures and prediction of therapy benefit in gastric cancer

Didi Wen, Kun Feng, Linbin Lu, Yongxi Song et al.
Cancer Biology and Medicine
Radiomics and Machine Learning in Medical Imaging
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A foundation model-enhanced CT radiomics signature for the noninvasive assessment of tertiary lymphoid structures and prediction of therapy benefit in gastric cancer

Didi Wen, Kun Feng, Linbin Lu, Yongxi Song, LW Chen, Jiangpeng Wei, Shibo Wang, Guang-Tao Wu, Zengshan Li, Zhongyang Zhang, J Yu, Xianchun Gao, Qiong Xiao, Ning Han, Yongzhan Nie, Zhe Li, Minwen Zheng, Yong Xia, Dai Zhang
article en

Abstract

Gastric cancer is a highly heterogeneous tumor type whose treatment responses substantially vary across patients. In recent years, biomarkers have shown promise in guiding individualized treatment regimens for gastric cancer, particularly for targeted therapy and immunotherapy[1][1]. Existing

Cancer Biology and Medicine
Northwestern Polytechnical University (CN), National Clinical Research Center for Digestive Diseases (CN), First Hospital of China Medical University (CN), Xijing Hospital (CN), China Medical University (CN), Air Force Medical University (CN)
Good health and well-being
Openalex Percentile: Top 17%
Radiomics and Machine Learning in Medical Imaging
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