Exploratory Evaluation of a Sodium Iodide-Based Root Canal Filling Formulation in a Canine Model of Enterococcus faecalis-Induced Periapical Inflammation
: NaI paste showed favorable early radiographic healing but limited long-term stability compared with conventional materials. With further optimization, it may have potential as an alternative root canal filling material. However, given the single-animal exploratory design, these findings should be interpreted as preliminary rather than definitive evidence.
Authors
- Jisun Shin (ORCID: https://orcid.org/0000-0003-2147-5163)
- Saeromi Jun
- Jung‐Hwan Lee (ORCID: https://orcid.org/0000-0001-8678-5459)
- Min-Cheol Song
- Yu-Jin Kim (ORCID: https://orcid.org/0000-0001-5219-1935)
Institutions
- Seoul National University (KR)
- New Generation University College (ET)
- Institute of Molecular Biology (AM)
- Seoul National University Dental Hospital (KR)
- Dankook University (KR)
Publication Details
- Journal
- Pharmaceutics
- Published
- 2026-04-17
- DOI
- https://doi.org/10.3390/pharmaceutics18040493
- Primary Topic
- Endodontics and Root Canal Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Dankook University