Carbene‐Catalyzed Enantioselective Synthesis of 1‐Oxyacylated‐2,4‐Disubstituted Cyclopentenes
Herein, we report the first carbene‐catalyzed enantioselective synthesis of multi‐functionalized oxyacylated cyclopentenes through [3 + 2] cycloaddition of α‐functionalized vinyl ketones and enals. The trisubstituted cyclopentenes were obtained with excellent enantioselectivity that could be readily converted to functionalized cyclopentenols.
Authors
- Hemlata Mourya
- Bal Krishna Mishra
- Bhoopendra Tiwari (ORCID: https://orcid.org/0000-0002-4187-3313)
- Kajal Verma
Institutions
- Centre of Biomedical Research (IN)
- Academy of Scientific and Innovative Research (IN)
Publication Details
- Journal
- European Journal of Organic Chemistry
- Published
- 2026-04-17
- DOI
- https://doi.org/10.1002/ejoc.70445
- Primary Topic
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Engineering Research Board