Regulatory T cell therapies: biological foundations, engineering strategies, and clinical translation

Tregs is now underway. This review provides a comprehensive and comparative analysis of the biological principles, engineering strategies, and translational challenges that shape the development of regulatory T cell-based immunotherapies.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-04-17
DOI
https://doi.org/10.3389/fimmu.2026.1797186
Primary Topic
CAR-T cell therapy research
Type
article
Field-Weighted Citation Impact
0.00
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article

Regulatory T cell therapies: biological foundations, engineering strategies, and clinical translation

Carole Guillonneau, Séverine Bézie, Charleen Plaisse
Frontiers in Immunology
CAR-T cell therapy research
article

Regulatory T cell therapies: biological foundations, engineering strategies, and clinical translation

Carole Guillonneau, Séverine Bézie, Charleen Plaisse
article en

Abstract

Tregs is now underway. This review provides a comprehensive and comparative analysis of the biological principles, engineering strategies, and translational challenges that shape the development of regulatory T cell-based immunotherapies.

Frontiers in ImmunologyVol. 17
Inserm (FR), Institut de Transplantation Urologie en Nephrologie (FR), Nantes Université (FR)
Openalex Percentile: Top 22%
CAR-T cell therapy research
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