Nanostructured Lipid Carriers Enhance Ciprofloxacin Antibacterial Activity Through Diffusion-Controlled Release and Modulation of Bacterial Growth Kinetics
Overall, these results show that NLC-based encapsulation can modulate ciprofloxacin release and reshape drug exposure over time, thereby improving antibacterial performance under the tested conditions. This study supports integrated release and growth-kinetic analyses as a more informative framework for evaluating lipid-based antibiotic delivery systems.
Authors
- Carlos F. Lagos (ORCID: https://orcid.org/0000-0002-5432-9747)
- Francisco Arriagada (ORCID: https://orcid.org/0000-0001-8404-6492)
- Javiera Carrasco-Rojas (ORCID: https://orcid.org/0000-0002-0711-433X)
- Andrea C. Ortiz (ORCID: https://orcid.org/0000-0001-9232-4632)
- F. Sandoval
- Lorena Rubio-Quiroz
- Javiera Solas-Soto
- Christina M. A. P. Schuh
Institutions
- Universidad del Desarrollo (CL)
- Clínica Alemana (CL)
- San Sebastián University (CL)
- Fundación Ciencia and Vida (CL)
- University of Chile (CL)
Publication Details
- Journal
- Pharmaceutics
- Published
- 2026-04-17
- DOI
- https://doi.org/10.3390/pharmaceutics18040496
- Primary Topic
- Advancements in Transdermal Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Comisión Nacional de Investigación Científica y Tecnológica