Phase Transitions of P(NIPAM- <i>g</i> -PLA) Copolymers in the Injectable Hydrogel Design
-PLA) were essentially modified by the presence of a biological buffer (PBS) as compared with pure water. An important finding of the study was the complete loss of the copolymer's ability to form gels due to aging (after a year-long storage). The potential influence of salts in biological buffers and the adverse effects of polymer aging should be considered when creating injectable hydrogels for biomedical applications.
Authors
- Yuri M. Efremov (ORCID: https://orcid.org/0000-0001-7040-253X)
- A. I. Frolova
- Svetlana Kotova (ORCID: https://orcid.org/0000-0001-7011-4503)
- Peter Timashev (ORCID: https://orcid.org/0000-0001-7773-2435)
- Sergei V. Kostjuk (ORCID: https://orcid.org/0000-0002-7466-3662)
- Valeriya Kukanova (ORCID: https://orcid.org/0009-0003-9645-9325)
- Yury A. Rochev
- Hanna A. Zhurauleva
Institutions
- Centre National de la Recherche Scientifique (FR)
- Science Foundation Ireland (IE)
- Sechenov University (RU)
- Ollscoil na Gaillimhe – University of Galway (IE)
- Belarusian State University (BY)
- Sorbonne Université (FR)
- Institut Parisien de Chimie Moléculaire (FR)
- Institute of Natural Science (KP)
- Applied Natural Sciences (US)
- Russian Academy of Natural Sciences (RU)
Publication Details
- Journal
- The Journal of Physical Chemistry B
- Published
- 2026-04-17
- DOI
- https://doi.org/10.1021/acs.jpcb.6c01426
- Primary Topic
- Hydrogels: synthesis, properties, applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Russian Science Foundation