The patterns of acetylcholinesterases during developmental stages of Aedes aegypti and their susceptibility toward insecticides in egg stage

, every metal tested had a partial inhibitory impact on the two enzymes. The most sensitive organophosphates and carbamates for inhibition of both enzymes were detected in eggs for the first time. For organophosphates and carbamates, the type of inhibition, bimolecular rate constant (Ki), and Ki ratio AChE1/AChE2 were detected. According to the findings, the Ki ratio AChE1/AChE2 toward methomyl, chlorpyrifos-methyl, and pirimiphos-methyl is less than 1.0, suggesting that both enzymes are more susceptible to inhibition by these insecticides. Eserine, malathion, and fenitrothion, on the other hand, have Ki ratios AChE1/AchE2 more than 1.0, indicating lower sensitivity. The study recommended using methomyl, pirimiphos-methyl, and chlorpyrifos-methyl to attack Ae. aegypti during the egg stage.