High-intensity interval training versus moderate-intensity continuous training for COPD: a systematics review and meta-analysis

BACKGROUND: Chronic Obstructive Pulmonary Disease(COPD) leads to reduced exercise capacity, lung function, and muscle dysfunction, highlighting the need for effective rehabilitation. Exercise is a key component of COPD management. PURPOSE: This study aims to compare the effectiveness of high-intensity interval training (HIIT) and Moderate-Intensity Continuous Training (MICT) on functional capacity, pulmonary function, and muscle performance in individuals with COPD. METHODS: Eight electronic databases were systematically searched from inception to August 2025. Data extraction and quality assessment were independently performed by two reviewers. Methodological quality was assessed using the PEDro scale and the JBI Critical Appraisal Checklist. The risk of bias was evaluated using the Cochrane Collaboration's Tool and the ROBINS-I tool. RESULTS: = .24). In terms of muscle function, HIIT provided greater benefits than MICT, including improvements in respiratory pressure, quadriceps endurance, handgrip strength, and muscle fiber composition. CONCLUSION: HIIT is superior to MICT in improving selected functional capacity outcomes and muscle function in COPD patients, and shows comparable effects to MICT in other functional measures. HIIT is a viable alternative training method; further research is needed to determine optimal protocols to maximize its benefits.