Psilocybin reshapes cortical inhibition through selective interneuron recruitment
receptor at SST interneurons, which contributes to the drug's long-term behavioral effects. Collectively, the results reveal that the classic psychedelic psilocybin alters cortical inhibition in a cell type-specific manner.
Authors
- Quan Jiang (ORCID: https://orcid.org/0000-0001-8201-6417)
- Alex C. Kwan (ORCID: https://orcid.org/0000-0003-2169-1667)
- Clara Liao (ORCID: https://orcid.org/0000-0003-2734-8202)
- A. M. Weiner (ORCID: https://orcid.org/0000-0002-4607-8570)
- Pasha A. Davoudian (ORCID: https://orcid.org/0000-0002-5096-7610)
- Neil K. Savalia (ORCID: https://orcid.org/0000-0003-2262-4466)
- Takeshi Sakurai (ORCID: https://orcid.org/0000-0003-4474-6253)
- Jack D. Nothnagel
- Cory A. Knox
- Catherine W Chong
- Ling-Xiao Shao (ORCID: https://orcid.org/0009-0006-9503-1230)
- Joshua Wilson (ORCID: https://orcid.org/0000-0002-6611-6941)
Institutions
- University of Tsukuba (JP)
- Cornell University (US)
- Yale University (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-04-17
- DOI
- https://doi.org/10.64898/2026.04.16.718963
- Primary Topic
- Psychedelics and Drug Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00