Mechanistic Insights into the Anti-Virulence Effects of Viroelixir, a Phenolic Blend from Green Tea and Pomegranate, on Streptococcus mutans
through a multi-target mechanism combining transcriptional suppression and predictive molecular inhibition of virulence proteins, supporting its potential as a safe, natural therapeutic for caries prevention.
Authors
- Mahmoud Rouabhia (ORCID: https://orcid.org/0000-0003-2205-8281)
- Mikhlid Hammad Almutairi (ORCID: https://orcid.org/0000-0002-0337-6412)
- Latifa Koussih
- Abdelhabib Semlali (ORCID: https://orcid.org/0000-0002-1643-0377)
- Manal Dahdah
- Hawraa Issa
- Yasmine Ettouil
- Vijaykumar D. Nimbarte (ORCID: https://orcid.org/0000-0002-4839-5705)
Institutions
- McGill University Health Centre (CA)
- King Saud University (SA)
- Birla Institute of Technology and Science - Hyderabad Campus (IN)
- Université Laval (CA)
- Université de Saint-Boniface (CA)
Publication Details
- Journal
- Antibiotics
- Published
- 2026-04-17
- DOI
- https://doi.org/10.3390/antibiotics15040406
- Citations
- 1
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 21.64
Funders
- Université Laval
- Réseau de Recherche en Santé Buccodentaire et Osseuse
- King Saud University
- Fonds de Recherche du Québec - Santé