Overweight/obesity accelerates proteinuria progression in type 2 diabetes post-COVID-19: a comparison with a pre-pandemic uninfected cohort

Aims: To assess whether overweight/obesity accelerates proteinuria progression in patients with type 2 diabetes mellitus (T2DM) after coronavirus disease 2019 (COVID-19) infection. Methods: ) groups. Proteinuria progression, defined as an increase in albuminuria stage, was assessed within three months pre- and post-infection. Multiple logistic regression analysis was used to evaluate the association between body weight status and proteinuria progression after COVID-19 infection. Results: increase in BMI was associated with a 13.1% increased risk of proteinuria progression after COVID-19 infection (OR, 1.131; 95% CI, 1.039 -1.23; P = 0.004). Conclusions: Overweight/obese accelerates proteinuria progression in patients with T2DM following COVID-19 infection. Therefore, emphasizing the importance of obesity management is crucial to prevent renal complications in patients with T2DM after COVID-19.