Brain tissue perfusion during pulmonary endarterectomy - The impact of controlled regional cooling
< 40%) occurred in 22.2% of Aurora patients versus 77.8% of Controls (p = 0.030). Postoperative NSE levels were lower in the Aurora group; however, the difference did not reach statistical significance (p = 0.087).ConclusionDual-modality cooling combining extracorporeal hypothermia and targeted head-neck cooling improved intraoperative cerebral oxygenation and were associated with lower postoperative NSE levels; however, due to the limited sample size, no definitive conclusions regarding neuronal injury can be drawn.
Authors
- Andrea Pellegrini (ORCID: https://orcid.org/0000-0002-3741-6531)
- Andrea Maria D’Armini (ORCID: https://orcid.org/0000-0002-7824-5249)
- Elisa Milanesi
- Monica Toscani
- Barbara Rossini
- Mirko Belliato (ORCID: https://orcid.org/0000-0002-3411-6293)
- Sara Bozzinì (ORCID: https://orcid.org/0000-0003-2819-732X)
- Federica Valsecchi
- Chiara Dezza
- Roberto Veronesi
Institutions
- Policlinico San Matteo Fondazione (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Perfusion
- Published
- 2026-04-16
- DOI
- https://doi.org/10.1177/02676591261429813
- Primary Topic
- Thermal Regulation in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00