A Preliminary Study on the Effects of Low Doses of Purified Zearalenone in Weaned Female Piglets: A Multi-Organ Toxicity Investigation

< 0.01), which progressed to histopathological damage in uterine and ovarian tissues at higher doses. These preliminary findings, together with significant correlations between oxidative stress markers and multi-organ parameters, suggest that low doses of purified ZEA may induce systemic oxidative stress and subclinical multi-organ toxicity in weaned female piglets, highlighting the need to incorporate redox status into risk assessment and to explore potential antioxidant-based mitigation strategies. However, given the small sample size, these results should be interpreted with caution and warrant validation in larger samples.

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Publication Details

Journal
Antioxidants
Published
2026-04-16
DOI
https://doi.org/10.3390/antiox15040496
Primary Topic
Mycotoxins in Agriculture and Food
Type
article
Field-Weighted Citation Impact
0.00
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article

A Preliminary Study on the Effects of Low Doses of Purified Zearalenone in Weaned Female Piglets: A Multi-Organ Toxicity Investigation

Sunlin Luo, Yuehua Chen, Wenjun He, Qiaomin Duan et al.
Antioxidants
Mycotoxins in Agriculture and Food
article

A Preliminary Study on the Effects of Low Doses of Purified Zearalenone in Weaned Female Piglets: A Multi-Organ Toxicity Investigation

Sunlin Luo, Yuehua Chen, Wenjun He, Qiaomin Duan, Ruiqi Tan, Wenjun Yang, Ying Liu
article en

Abstract

< 0.01), which progressed to histopathological damage in uterine and ovarian tissues at higher doses. These preliminary findings, together with significant correlations between oxidative stress markers and multi-organ parameters, suggest that low doses of purified ZEA may induce systemic oxidative stress and subclinical multi-organ toxicity in weaned female piglets, highlighting the need to incorporate redox status into risk assessment and to explore potential antioxidant-based mitigation strategies. However, given the small sample size, these results should be interpreted with caution and warrant validation in larger samples.

AntioxidantsVol. 15(4)
Ministry of Agriculture and Rural Affairs (CN), China Agricultural University (CN)
Openalex Percentile: Top 21%
Mycotoxins in Agriculture and Food
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