<i>HBA2</i> Gene Conversion Disrupts Reverse Dot-Blot Hybridization Genotyping: A Prenatal Case of Non-Deletional α-Thalassemia Misdiagnosis
α, respectively. This study elucidated a molecular mechanism of gene conversion that complicates the diagnosis of α-globin gene clusters, providing critical evidence for clinical genetic counseling and prenatal diagnosis.
Authors
- Qingyan Zhong
- Cheng Huang (ORCID: https://orcid.org/0000-0001-8220-1815)
- Meiyu Zhang (ORCID: https://orcid.org/0000-0003-4634-6800)
- Dejian Yuan (ORCID: https://orcid.org/0000-0001-9884-2158)
- Lizhu Chen
- Xiaobao Wei
- Jun Huang
- Xiaoli Liu
Institutions
- Liuzhou Maternal and Child Health Hospital (CN)
- Guangzhou Women and Children Medical Center (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Hemoglobin
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1080/03630269.2026.2653219
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00