A deep learning based NeuroFusionNet approach for automated brain tumor diagnosis from MRI
Background: Brain tumor diagnosis from magnetic resonance imaging (MRI) remains a challenging task due to the high variability in tumor appearance and the limitations of manual interpretation. Methods: To address these challenges, this paper proposes NeuroFusionNet, a deep learning framework for automated brain tumor classification from MRI. The framework integrates GAN-based synthetic image generation with transfer learning using a fine-tuned VGG16 backbone. Real and GAN-generated MRI images are passed through VGG16 to extract discriminative feature representations, which are then used for final classification. To adapt the model to domain-specific MRI characteristics while preserving pretrained knowledge, the last ten layers of VGG16 are fine-tuned and the remaining layers are kept frozen. Results: The effectiveness of NeuroFusionNet is validated on two publicly available brain MRI datasets. Experimental results demonstrate that the proposed learning framework achieves classification accuracies of 99.05 and 98.75% on the Brain Tumor MRI Dataset and the MRI with Bounding Boxes Dataset, respectively, consistently outperforming several state-of-the-art neural architectures, including VGG16, VGG19, MobileNetV2, DenseNet121, and NASNetLarge. Conclusion: The results suggest that NeuroFusionNet is effective for the evaluated public MRI datasets; additional external validation is required.
Authors
- Hanan Akhdar (ORCID: https://orcid.org/0000-0001-5144-7169)
- Hamad Yahia Abu Mhanna (ORCID: https://orcid.org/0000-0001-6629-3297)
- Abdel-Baset Bani Yaseen
- Majd Malkawi
- Abdallah Almahmoud
- Mohammad Amin (ORCID: https://orcid.org/0009-0009-9044-8178)
- Salem Alhatamleh
- Fatimah Maashey
- Latifah Alghulayqah
- Rami Malkawi
- Omara Mustafa
- Hatem Malkawi
Institutions
- University of Medical Sciences and Technology (SD)
- Jordan University of Science and Technology (JO)
- Hashemite University (JO)
- Isra University (PK)
- Al Yarmouk University College (IQ)
- Yarmouk Private University (SY)
- Islamic University (BD)
- Dunsan Korean Medicine Hospital (KR)
- Yarmouk University (JO)
Publication Details
- Journal
- Frontiers in Neuroinformatics
- Published
- 2026-04-16
- DOI
- https://doi.org/10.3389/fninf.2026.1795354
- Primary Topic
- Brain Tumor Detection and Classification
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Al-Imam Muhammad Ibn Saud Islamic University