Peroxiredoxin Ⅲ safeguards cardiac function against doxorubicin by regulating mitochondrial quality control via H2O2 detoxification
as a pivotal determinant in DOX-induced mitochondrial dysfunction and cardiotoxicity, highlighting PrxⅢ as a promising therapeutic target for mitigating oxidative cardiac injury.
Authors
- Okhee Kweon
- Ho Jin Yi (ORCID: https://orcid.org/0000-0002-9367-6223)
- Hyun Ae Woo (ORCID: https://orcid.org/0000-0002-3483-1203)
- Goo Taeg Oh (ORCID: https://orcid.org/0000-0002-1104-1698)
- Tong‐Shin Chang (ORCID: https://orcid.org/0000-0003-4472-5436)
- Ji Won Park (ORCID: https://orcid.org/0000-0001-9661-3220)
- Se Yeon Jang
- Mi Yeon Kim (ORCID: https://orcid.org/0000-0002-5544-1343)
- Seong Keun Sonn
- Byung-Hoon Lee
Institutions
- Ewha Womans University (KR)
- Seoul National University (KR)
Publication Details
- Journal
- Redox Biology
- Published
- 2026-04-17
- DOI
- https://doi.org/10.1016/j.redox.2026.104176
- Primary Topic
- Redox biology and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Education
- Ministry of Science and ICT, South Korea