Metformin Use and Clinical Outcomes in Very Elderly Patients with Type 2 Diabetes and Chronic Kidney Disease

In very elderly patients with CKD and type 2 diabetes, metformin use was associated with a higher observed risk of adverse clinical outcomes. These findings support a cautious, individualized risk-benefit assessment when prescribing metformin in this population.

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Publication Details

Journal
Medicina
Published
2026-04-16
DOI
https://doi.org/10.3390/medicina62040776
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Metformin Use and Clinical Outcomes in Very Elderly Patients with Type 2 Diabetes and Chronic Kidney Disease

Michele Marchini
Medicina
Diabetes Treatment and Management
article

Metformin Use and Clinical Outcomes in Very Elderly Patients with Type 2 Diabetes and Chronic Kidney Disease

Michele Marchini
article en

Abstract

In very elderly patients with CKD and type 2 diabetes, metformin use was associated with a higher observed risk of adverse clinical outcomes. These findings support a cautious, individualized risk-benefit assessment when prescribing metformin in this population.

MedicinaVol. 62(4)
NATO Centre for Maritime Research and Experimentation (IT)
Good health and well-being
Openalex Percentile: Top 26%
Diabetes Treatment and Management
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