Establishment and validation of a risk scoring model for predicting the risk of bladder stones in patients with benign prostatic hyperplasia

Purpose: The aim of this study is to identify independent risk factors for bladder stones in patients with benign prostatic hyperplasia (BPH), and to develop and validate a nomogram prediction model for assessing the risk of bladder stones in this patient population. Methods: Retrospective analysis included 446 BPH patients (106 with bladder stones, 340 without) who underwent transurethral resection of the prostate (2023-2025). Univariate ROC (receiver operating characteristic), correlation analysis, LASSO regression, and multivariate logistic regression were used for variable screening and model construction. The cohort was split into training (70%) and validation (30%) sets. Model performance was evaluated via AUC (discrimination), calibration curves, Hosmer-Lemeshow test (calibration), and DCA (clinical utility). Results: > 0.05), and robust clinical utility. Conclusion: The nomogram overcomes univariate and multicollinearity limitations, enabling precise individualized risk assessment of bladder stones in BPH patients. It serves as a reliable tool for clinicians to guide personalized monitoring and prevention, potentially reducing incidence and healthcare burdens.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-04-16
DOI
https://doi.org/10.3389/fmed.2026.1795565
Primary Topic
Urinary Bladder and Prostate Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Establishment and validation of a risk scoring model for predicting the risk of bladder stones in patients with benign prostatic hyperplasia

Hongzhi Fang, Yi Luo, Yi Gao, Changjian Shi et al.
Frontiers in Medicine
Urinary Bladder and Prostate Research
article

Establishment and validation of a risk scoring model for predicting the risk of bladder stones in patients with benign prostatic hyperplasia

Hongzhi Fang, Yi Luo, Yi Gao, Changjian Shi, Yunfei Li, Jie Xu, Xinyi Li
article en

Abstract

Purpose: The aim of this study is to identify independent risk factors for bladder stones in patients with benign prostatic hyperplasia (BPH), and to develop and validate a nomogram prediction model for assessing the risk of bladder stones in this patient population. Methods: Retrospective analysis included 446 BPH patients (106 with bladder stones, 340 without) who underwent transurethral resection of the prostate (2023-2025). Univariate ROC (receiver operating characteristic), correlation analysis, LASSO regression, and multivariate logistic regression were used for variable screening and model construction. The cohort was split into training (70%) and validation (30%) sets. Model performance was evaluated via AUC (discrimination), calibration curves, Hosmer-Lemeshow test (calibration), and DCA (clinical utility). Results: > 0.05), and robust clinical utility. Conclusion: The nomogram overcomes univariate and multicollinearity limitations, enabling precise individualized risk assessment of bladder stones in BPH patients. It serves as a reliable tool for clinicians to guide personalized monitoring and prevention, potentially reducing incidence and healthcare burdens.

Frontiers in MedicineVol. 13
Wuhan University (CN), Renmin Hospital of Wuhan University (CN)
Natural Science Foundation of Hubei Province
Reduced inequalities, Peace, Justice and strong institutions
Openalex Percentile: Top 24%
Urinary Bladder and Prostate Research
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