Multiple lung metastases from typical type A thymoma after long-term follow-up: a case report

BACKGROUND: Typical type A thymomas are slow-growing tumors generally associated with a favorable clinical course, and distant metastasis is exceedingly rare. CASE PRESENTATION: We report a case of multiple lung metastases from a typical type A thymoma in a 74-year-old man, identified 9 years after the initial detection of an anterior mediastinal nodule. The patient underwent simultaneous thymectomy and wedge resection of the pulmonary nodule. Histopathological examination confirmed a diagnosis of typical type A thymoma with pulmonary metastases. Postoperatively, the patient was also diagnosed with prostate cancer as a secondary malignancy. At 2-year follow-up, without any postoperative treatment, there was no evidence of progression or development of new pulmonary lesions. CONCLUSION: This case underscores the potential for distant metastasis in patients with otherwise indolent, typical type A thymomas, highlighting the need for long-term surveillance.

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Publication Details

Journal
Journal of Cardiothoracic Surgery
Published
2026-04-16
DOI
https://doi.org/10.1186/s13019-026-04045-5
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
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article

Multiple lung metastases from typical type A thymoma after long-term follow-up: a case report

Atsushi Sano, Keita Tobari, Tsuyoshi Takahashi
Journal of Cardiothoracic Surgery
Myasthenia Gravis and Thymoma
article

Multiple lung metastases from typical type A thymoma after long-term follow-up: a case report

Atsushi Sano, Keita Tobari, Tsuyoshi Takahashi
article en

Abstract

BACKGROUND: Typical type A thymomas are slow-growing tumors generally associated with a favorable clinical course, and distant metastasis is exceedingly rare. CASE PRESENTATION: We report a case of multiple lung metastases from a typical type A thymoma in a 74-year-old man, identified 9 years after the initial detection of an anterior mediastinal nodule. The patient underwent simultaneous thymectomy and wedge resection of the pulmonary nodule. Histopathological examination confirmed a diagnosis of typical type A thymoma with pulmonary metastases. Postoperatively, the patient was also diagnosed with prostate cancer as a secondary malignancy. At 2-year follow-up, without any postoperative treatment, there was no evidence of progression or development of new pulmonary lesions. CONCLUSION: This case underscores the potential for distant metastasis in patients with otherwise indolent, typical type A thymomas, highlighting the need for long-term surveillance.

Journal of Cardiothoracic Surgery
Toho University (JP), Toho University Medical Center Sakura Hospital (JP)
Good health and well-being
Openalex Percentile: Top 12%
Myasthenia Gravis and Thymoma
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