A call for preregistration of in vitro research
This article highlights the benefits of preregistration in improving the reliability and transparency of in vitro studies. By preregistering their studies, researchers can make their findings more reproducible, paving the way for medical progress, and accelerating the replacement of animal experiments.
Authors
- Ulf D. Kahlert (ORCID: https://orcid.org/0000-0002-6021-1841)
- Manosij Ghosh (ORCID: https://orcid.org/0000-0001-5034-001X)
- Katherina Siewert (ORCID: https://orcid.org/0000-0003-0380-1594)
- Nuno Henrique Franco (ORCID: https://orcid.org/0000-0003-4015-0532)
- Winfried Neuhaus (ORCID: https://orcid.org/0000-0002-6552-7183)
- Bettina Bert (ORCID: https://orcid.org/0000-0002-8202-9290)
- Céline Heinl
- Carina Ladeira (ORCID: https://orcid.org/0000-0001-5588-0074)
- Athanassia Sotiropoulos (ORCID: https://orcid.org/0000-0002-7265-1473)
- Dania Movia (ORCID: https://orcid.org/0000-0001-6412-8132)
- Ahmed Y. Sanin (ORCID: https://orcid.org/0009-0009-7786-2200)
- Aurélie Thomas (ORCID: https://orcid.org/0000-0003-1655-3278)
- Edlira Aruçi (ORCID: https://orcid.org/0009-0009-3412-526X)
Institutions
- University of Siena (IT)
- AstraZeneca (United Kingdom) (GB)
- Danube Private University (AT)
- AIT Austrian Institute of Technology GmbH (AT)
- Inserm (FR)
- National University of Ireland, Maynooth (IE)
- Universidade Politécnica de Lisboa (PT)
- Trinity College (CA)
- Trinity College Dublin (IE)
- Federal Institute for Risk Assessment (DE)
- AstraZeneca (South Korea) (KR)
- National School of Public Health (GR)
- Agence Nationale des Fréquences (FR)
- University Hospital Magdeburg (DE)
- i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto (PT)
- Otto-von-Guericke-Universität Magdeburg (DE)
- KU Leuven (BE)
Publication Details
- Journal
- EMBO Reports
- Published
- 2026-04-17
- DOI
- https://doi.org/10.1038/s44319-026-00764-x
- Primary Topic
- Animal testing and alternatives
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Cooperation in Science and Technology