Septic Shock and Severe AKI Caused by West Nile Virus in Southern France

West Nile virus (WNV) is a neurotropic orthoflavivirus primarily transmitted by Culex mosquitoes and, rarely, through blood transfusion or organ transplantation. Birds constitute the main reservoir, while humans and horses are considered dead-end hosts.1 In 2025, 1,112 locally acquired WNV cases were reported across 14 European countries, including 62 in France, 31% of which occurred in the Bouches-du-Rhône department in southern France.2

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Publication Details

Journal
Kidney International Reports
Published
2026-04-17
DOI
https://doi.org/10.1016/j.ekir.2026.106544
Primary Topic
Mosquito-borne diseases and control
Type
article
Field-Weighted Citation Impact
0.00

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article

Septic Shock and Severe AKI Caused by West Nile Virus in Southern France

Nadim Cassir, Esther Cortes, Anna Crepet, Xavier De Lamballerie et al.
Kidney International Reports
Mosquito-borne diseases and control
article

Septic Shock and Severe AKI Caused by West Nile Virus in Southern France

Nadim Cassir, Esther Cortes, Anna Crepet, Xavier De Lamballerie, Nazli Ayhan, Raphaelle Klitting, Guillaume Durand, Mickaël Bobot, Laura Pezzi
article en

Abstract

West Nile virus (WNV) is a neurotropic orthoflavivirus primarily transmitted by Culex mosquitoes and, rarely, through blood transfusion or organ transplantation. Birds constitute the main reservoir, while humans and horses are considered dead-end hosts.1 In 2025, 1,112 locally acquired WNV cases were reported across 14 European countries, including 62 in France, 31% of which occurred in the Bouches-du-Rhône department in southern France.2

Kidney International ReportsVol. 11(6)
Inserm (FR), Aix-Marseille Université (FR), Méditerranée Infection Foundation (FR), Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR), Hôpital de la Conception (FR), Hôpital Privé Jacques Cartier (FR), Institut de Recherche pour le Développement (FR)
Aix-Marseille Université, Institut National de la Santé et de la Recherche Médicale
Good health and well-being
Openalex Percentile: Top 23%
Mosquito-borne diseases and control
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