Preventive Care and Early Intervention Strategies for Obesity, Diabetes and Cardiovascular Disease
The prevalence of obesity, diabetes mellitus, and cardiovascular disease (CVD), is increasing worldwide due to rapid urbanization, lifestyle changes, and an ageing population. All three conditions share a common pathological basis characterized by features of insulin resistance, chronic inflammation and disturbed metabolic function that together account for a major component of morbidity, mortality and increasing healthcare expenditure. A wide range of risk factors contribute to metabolic disorders, including modifiable behavioural risk factors such as diet and physical activity, as well as non-modifiable and socio-environmental risks. Primary prevention can be achieved through lifestyle modification and health education programmes. Secondary prevention relies on early detection and screening of at-risk individuals using simple tests such as BMI, fasting glucose levels, HbA1c, lipid profiles and cardiovascular risk scores. This review utilizes a narrative synthesis to discuss evidence-based approaches to preventive care for these major health problems, including multidisciplinary treatment pathways for effective obesity, diabetes and CVD prevention. It also explores emerging innovations such as digital health technologies, artificial intelligence and precision medicine and their potential in future prevention programs. The review addresses critical barriers at the individual, healthcare system and policy levels, as well as a discussion of cost-effective interventions in low-resource settings to prevent these conditions among diverse populations. To successfully address the global epidemics of obesity, diabetes and CVD, an integrated, multi-level approach that seeks behaviour change at the individual level, strengthens the healthcare system, and supports appropriate public policies at the population level is required.
Authors
- Obinna Hilary Tony-Okpalaobi
- Peter Aduvie Josiah
- Bukola Mekuleyi Asorho (ORCID: https://orcid.org/0009-0008-8885-6749)
- Collins E. Ihebie (ORCID: https://orcid.org/0000-0001-7523-5806)
- Eberechi Ogeiheoma Nwoye (ORCID: https://orcid.org/0009-0001-1387-9443)
- Ganiyat Titilayo Raji (ORCID: https://orcid.org/0009-0004-5232-3618)
Institutions
- Niger Delta University (NG)
- West Chester University (US)
- Nnamdi Azikiwe University (NG)
- University Hospitals of North Midlands NHS Trust (GB)
- Federal Medical Centre (NG)
- Ladoke Akintola University of Technology (NG)
Publication Details
- Journal
- Journal of Disease and Global Health
- Published
- 2026-04-16
- DOI
- https://doi.org/10.56557/jodagh/2026/v19i110481
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00