Distinct cytokines regulate gene expression and anti-tumor activity in regenerated CD8+ T cells from induced pluripotent stem cells

Authors

Daisuke Okuzaki (ORCID: https://orcid.org/0000-0002-4552-783X)
Yasutoshi Agata (ORCID: https://orcid.org/0000-0001-9642-6994)
Masaji Tani (ORCID: https://orcid.org/0000-0003-1270-6003)
Koji Terada
Mina Kumode
Nobuhito Nitta
Kenta Kondo
Hiroshi Kawamoto
Kyoko Masuda
Yusuke Sano
Toru Miyake
Seiji Nagano

Institutions

Shiga University of Medical Science (JP)
Kyoto University (JP)
The University of Osaka (JP)

Publication Details

Journal: iScience
Published: 2026-04-16
DOI: https://doi.org/10.1016/j.isci.2026.115756
Primary Topic: Pluripotent Stem Cells Research
Type: article
Field-Weighted Citation Impact: 0.00

Funders

Bristol-Myers Squibb
Naito Foundation
Suzuken Memorial Foundation
Takeda Science Foundation
Japan Cancer Society
Kyoto University
SENSHIN Medical Research Foundation
Terumo Foundation for Life Sciences and Arts
Japan Society for the Promotion of Science

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article

Distinct cytokines regulate gene expression and anti-tumor activity in regenerated CD8+ T cells from induced pluripotent stem cells

Daisuke Okuzaki, Yasutoshi Agata, Masaji Tani, Koji Terada et al.

Apr 16, 2026

iScience

Pluripotent Stem Cells Research

article

Distinct cytokines regulate gene expression and anti-tumor activity in regenerated CD8+ T cells from induced pluripotent stem cells

Daisuke Okuzaki, Yasutoshi Agata, Masaji Tani, Koji Terada, Mina Kumode, Nobuhito Nitta, Kenta Kondo, Hiroshi Kawamoto, Kyoko Masuda, Yusuke Sano, Toru Miyake, Seiji Nagano

April 16, 2026article en

Abstract

No abstract available for this paper.

iScienceVol. 29(5)

Shiga University of Medical Science (JP), Kyoto University (JP), The University of Osaka (JP)

Bristol-Myers Squibb, Naito Foundation, Suzuken Memorial Foundation, Takeda Science Foundation, Japan Cancer Society, Kyoto University, SENSHIN Medical Research Foundation, Terumo Foundation for Life Sciences and Arts, Japan Society for the Promotion of Science

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Pluripotent Stem Cells Research

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