Unicentric Castleman Disease in the neck: a case report

The aim of this report is to present a case of unicentric hyaline vascular Castleman disease in the neck and to discuss its treatment in the light of the current literature. A 52-year-old man presented with a painless, non-progressive swelling in the right submandibular region for one year. Physical examination revealed a 2 × 3 cm firm, fixed mass located outside the submandibular gland. Radiological tests identified a well-circumscribed lesion located outside the submandibular gland. As lymphoid cells were reported in fine-needle aspiration cytology, an excisional biopsy was performed and hyaline vascular Castleman disease was diagnosed. As the disease was unicentric, no further treatment was planned, and the patient was taken into follow-up. During five years of clinical and radiological follow-up, there was no evidence of recurrence.

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Journal
Interdisciplinary Medical Journal
Published
2026-04-16
DOI
https://doi.org/10.17944/interdiscip.1748748
Primary Topic
Viral-associated cancers and disorders
Type
article
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article

Unicentric Castleman Disease in the neck: a case report

Şermin Özkal, Mehmet Ali Ozcan, Aslı Çakır Çeti̇n, Nuri Karabay et al.
Interdisciplinary Medical Journal
Viral-associated cancers and disorders
article

Unicentric Castleman Disease in the neck: a case report

Şermin Özkal, Mehmet Ali Ozcan, Aslı Çakır Çeti̇n, Nuri Karabay, Ahmet Ömer İkiz, Ömer Faruk Zengin
article en

Abstract

The aim of this report is to present a case of unicentric hyaline vascular Castleman disease in the neck and to discuss its treatment in the light of the current literature. A 52-year-old man presented with a painless, non-progressive swelling in the right submandibular region for one year. Physical examination revealed a 2 × 3 cm firm, fixed mass located outside the submandibular gland. Radiological tests identified a well-circumscribed lesion located outside the submandibular gland. As lymphoid cells were reported in fine-needle aspiration cytology, an excisional biopsy was performed and hyaline vascular Castleman disease was diagnosed. As the disease was unicentric, no further treatment was planned, and the patient was taken into follow-up. During five years of clinical and radiological follow-up, there was no evidence of recurrence.

Interdisciplinary Medical JournalVol. 17(57)
Ordu University (TR)
Openalex Percentile: Top 15%
Viral-associated cancers and disorders
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Unicentric Castleman Disease in the neck: a case report — Şermin Özkal, Mehmet Ali Ozcan, et al. · Interdisciplinary Medical Journal (2026) | TGRS Research Map | TGRS