Biological Consequences of Single and Combined Exposure to Magnetite–Chitosan Nanocomposite with Adsorbed Cobalt (II) in Danio rerio
and MDA levels. The study found that MCN alone did not lead to mortality or increase peroxide levels or lipid peroxidation, although a modest decrease in SOD activity was observed. In contrast, combined exposure to cobalt and MCN resulted in significant delayed mortality (>85% at 96 h) and early neuromotor impairment. These findings indicate that high abiotic sorption efficiency alone does not guarantee reduced biological toxicity when nanomaterial-metal interactions occur. Consequently, safety assessments of remediation nanomaterials should explicitly consider nanomaterial-metal interactions and developmental stage-specific biological responses.
Authors
- Živilė Jurgelėnė
- Martynas Talaikis (ORCID: https://orcid.org/0000-0003-3516-6425)
- Sergej Šemčuk (ORCID: https://orcid.org/0000-0001-8922-6687)
- Kęstutis Mažeika (ORCID: https://orcid.org/0000-0003-4792-8650)
- Galina Lujanienė (ORCID: https://orcid.org/0000-0002-1894-6086)
- Justas Lazutka (ORCID: https://orcid.org/0000-0003-2006-7280)
- Danguolė Montvydienė (ORCID: https://orcid.org/0000-0002-8664-2746)
- Renata Butrimienė
- Vidas Pakštas (ORCID: https://orcid.org/0000-0002-4282-0213)
- Aida Bradauskaitė (ORCID: https://orcid.org/0009-0007-0097-7996)
Institutions
- Vilnius University (LT)
- Center for Physical Sciences and Technology (LT)
- Nature Research Centre (LT)
Publication Details
- Journal
- Biology
- Published
- 2026-04-16
- DOI
- https://doi.org/10.3390/biology15080624
- Primary Topic
- Nanoparticles: synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Lietuvos Mokslo Taryba