Distribution of adult T‐cell leukaemia/lymphoma subtypes and survival outcomes across geographical regions: An international retrospective cohort study
< 0.0001). With a median follow-up of 38 months interquartile range (IQR 14-68), 3-year OS across regions ranged from 10% to 25% for acute, 16%-34% for lymphomatous, 49%-86% for chronic and 60%-83% for smouldering ATL. Evidence of regional differences in OS was observed for acute, lymphomatous and chronic ATL but not for smouldering ATL. In conclusion, the distribution of ATL subtypes varies globally, and OS for aggressive subtypes (i.e. acute and aggressive) remains poor across regions. Our findings could guide the design of clinical studies aimed at developing accessible therapies through international collaboration.
Authors
- Britney Bell
- Thanya Runciman (ORCID: https://orcid.org/0000-0003-3915-4886)
- Daniel La Rosa
- Oriana Arias
- Bryan Valcárcel (ORCID: https://orcid.org/0000-0003-3853-2603)
- Hiroo Katsuya (ORCID: https://orcid.org/0000-0003-1498-4357)
- Atae Utsunomiya (ORCID: https://orcid.org/0000-0002-8843-406X)
- Yasushi Takamatsu (ORCID: https://orcid.org/0000-0003-4246-9969)
- Camila Peña (ORCID: https://orcid.org/0000-0002-8076-2077)
- Lorena Fiad
- Maki Otsuka
- Masaharu Miyahara
- EC Miranda
- Henry Idrobo (ORCID: https://orcid.org/0000-0002-7686-5874)
- Elizabeth Arrieta
- Gabriela Garrido-Pinzas (ORCID: https://orcid.org/0000-0002-6930-8893)
- Junji Suzumiya
- Denisse Castro (ORCID: https://orcid.org/0000-0002-5108-9493)
- Luis Malpica
- Victor Rivera
- Jose Sandoval-Sus
- Daniel Enriquez‐Vera
- Alejandro Sica
- Kazuo Tamura
- Brady E. Beltran
- Lucy B. Cook
- Veronica Leataud
- Jule F. Vasquez
- Juan C. Ramos
- Kenji Ishitsuka
- Eduardo Gotuzzo
- Carlos Chiattone
Institutions
- Boston University (US)
- Montefiore Medical Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- University of Miami (US)
- Imperial College Healthcare NHS Trust (GB)
- Saga University (JP)
- Universidade Estadual de Campinas (UNICAMP) (BR)
- Universidad Peruana Cayetano Heredia (PE)
- Technological University of Pereira (CO)
- Universidad Privada San Juan Bautista (PE)
- Universidad San Ignacio de Loyola (PE)
- Hammersmith Hospital (GB)
- Fukuoka University (JP)
- Hospital Nacional Cayetano Heredia (PE)
- Hospital Samaritano de São Paulo (BR)
- Memorial Healthcare System (US)
- Fundación Valle del Lili (CO)
- Hospital del Salvador (CL)
- Red Cross Hospital (GR)
- Hospital Italiano La Plata (AR)
- Kagoshima University Hospital (JP)
- Universidad Católica de Pereira (CO)
- Koga Hospital (JP)
- Instituto Nacional de Enfermedades Neoplásicas (PE)
- Imamura Hospital (JP)
- Kagoshima Medical Center (JP)
- Hospital de Clínicas da Unicamp (BR)
- Hospital Base Guillermo Almenara Irigoyen (PE)
- St Martins Hospital (GB)
Publication Details
- Journal
- British Journal of Haematology
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1111/bjh.70494
- Primary Topic
- T-cell and Retrovirus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00