Clinical Outcomes of Peptide Receptor Radionuclide Therapy in Japanese Patients with Metastatic Rectal Neuroendocrine Tumors
: PRRT may provide durable disease control with a favorable safety profile in Japanese patients with metastatic rectal NETs. However, these findings should be interpreted with caution given the small sample size and heterogeneous patient population. Baseline NSE elevation and early post-treatment declines may serve as potential prognostic indicators. These results are hypothesis-generating and warrant validation in larger, multicenter studies.
Authors
- Sho Tsuyuki (ORCID: https://orcid.org/0009-0000-1026-7778)
- Felix Kaul
- Damian Wild (ORCID: https://orcid.org/0000-0002-8135-5350)
- N Kobayashi
- Masato Yoneda (ORCID: https://orcid.org/0000-0001-7815-549X)
- Yusuke Kurita (ORCID: https://orcid.org/0000-0003-2482-6707)
- Takeshi Iizuka
- Shoko Takano (ORCID: https://orcid.org/0000-0002-4289-6250)
- Kengo Maehara
- Naoki Okubo
- Yasushi Ichikawa
- Hiroaki Suzuki
Institutions
- University Hospital of Basel (CH)
- Yokohama City University Hospital (JP)
- Yokohama City University (JP)
Publication Details
- Journal
- Cancers
- Published
- 2026-04-16
- DOI
- https://doi.org/10.3390/cancers18081268
- Primary Topic
- Neuroendocrine Tumor Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00