Influence of Chondroitin Sulfate Concentration on the Physicochemical Properties of Acetaminophen-Releasing Cellulose/PVOH Membranes
. Drug release studies demonstrated a diffusion-controlled kinetic profile for acetaminophen. This work presents a simple method for fabricating membranes with desirable physicochemical and structural properties, highlighting their potential for use as bioactive dressings and transdermal drug delivery systems.
Authors
- Gizilene Maria de Carvalho (ORCID: https://orcid.org/0000-0001-9514-7897)
- Paulo Rodrigo Stival Bittencourt (ORCID: https://orcid.org/0000-0001-8740-1672)
- Jéssica Bassetto Carra (ORCID: https://orcid.org/0000-0003-0400-7413)
- Paula Paulino Silva (ORCID: https://orcid.org/0000-0002-4883-6654)
- Rúbia Casagrande (ORCID: https://orcid.org/0000-0002-2296-1668)
- Juliano Brisola (ORCID: https://orcid.org/0000-0003-0369-8013)
- Francisnara Tonholi
Institutions
- Universidade Estadual de Londrina (BR)
- Universidade Tecnológica Federal do Paraná (BR)
Publication Details
- Journal
- ACS Omega
- Published
- 2026-04-16
- DOI
- https://doi.org/10.1021/acsomega.6c01092
- Primary Topic
- Hydrogels: synthesis, properties, applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação Araucária
- Universidade Tecnológica Federal do Paraná