How Long to Treat to Achieve Desired Treatment Outcomes with Baricitinib 4 mg in Severe Alopecia Areata: Evidence-based Approach
INTRODUCTION: ) and subsequent treatment success (SALT score ≤ 20) in four subgroups defined by baseline disease severity and AA episode duration to inform the treatment length required before assessing failure, based on disease presentation. METHODS: and subsequent SALT score ≤ 20 over time. RESULTS: achieved in 42%/25% of patients by Week 24, leading to SALT score ≤ 20 in 58%/43% at Week 52, respectively. CONCLUSIONS: increased through Week 52; therefore, treatment should be given for ≥ 1 year before assessing treatment failure.
Authors
- Manabu Ohyama (ORCID: https://orcid.org/0000-0002-2662-5717)
- Bianca Maria Piraccini (ORCID: https://orcid.org/0000-0001-6537-9689)
- Najwa Somani
- King Bl
- Yun-Fei Chen
- Rodney Sinclair
- Andrew Buchanan
- Jakub Jedynak
- Na Lu
- Maryanne Senna
Institutions
- Lahey Hospital and Medical Center (US)
- Eli Lilly (United States) (US)
- Kyorin University (JP)
- Yale University (US)
- Sinclair Dermatology (AU)
- University of Bologna (IT)
Publication Details
- Journal
- Dermatology and Therapy
- Published
- 2026-04-16
- DOI
- https://doi.org/10.1007/s13555-026-01723-z
- Primary Topic
- Hair Growth and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Eli Lilly and Company
- Incyte