Covalent Immobilization of Hydrogels on Carbon Fiber Microelectrodes for the Determination of Dopamine in the Living Mouse Brain
-pTA/CFE facilitated real-time dynamic monitoring of DA release in the striatum of a living mouse. The present study proposes a systematic screening paradigm for the rational design of functionalized electrode interfaces, thus extending the application of the oriented covalent immobilization in situ hydrogel coating strategy to in vivo neurochemical analysis.
Authors
- Jiatao Chen
- D H Zhang
- Xinxin Zhao (ORCID: https://orcid.org/0000-0002-1347-9503)
- Fuyun Xia
- Meilin Shi
- Buyi Wang
Institutions
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- ACS Applied Bio Materials
- Published
- 2026-04-16
- DOI
- https://doi.org/10.1021/acsabm.6c00410
- Primary Topic
- Electrochemical sensors and biosensors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China