Disparities in paediatric-eligible vitiligo clinical trials

In a cross-sectional analysis of completed paediatric-eligible vitiligo trials, we evaluated reporting of race/ethnicity, Fitzpatrick skin type and age using data from ClinicalTrials.gov and associated publications. Among 10 trials enrolling 1475 participants, demographic reporting was inconsistent, with most participants being White, limited representation of individuals with skin of colour and no age stratification for children younger than 13 years. These findings highlight persistent under-reporting and under-representation in paediatric vitiligo research, underscoring the need for standardized demographic reporting and more inclusive recruitment strategies.

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Publication Details

Journal
Clinical and Experimental Dermatology
Published
2026-04-11
DOI
https://doi.org/10.1093/ced/llag166
Primary Topic
melanin and skin pigmentation
Type
article
Field-Weighted Citation Impact
0.00
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article

Disparities in paediatric-eligible vitiligo clinical trials

K.C. Gupta, Chiara Tognaccini, Jashin J. Wu, Michael Ghebrial et al.
Clinical and Experimental Dermatology
melanin and skin pigmentation
article

Disparities in paediatric-eligible vitiligo clinical trials

K.C. Gupta, Chiara Tognaccini, Jashin J. Wu, Michael Ghebrial, Dina Ghanim, Leah E. Thomas, Zahra Ansari
article en

Abstract

In a cross-sectional analysis of completed paediatric-eligible vitiligo trials, we evaluated reporting of race/ethnicity, Fitzpatrick skin type and age using data from ClinicalTrials.gov and associated publications. Among 10 trials enrolling 1475 participants, demographic reporting was inconsistent, with most participants being White, limited representation of individuals with skin of colour and no age stratification for children younger than 13 years. These findings highlight persistent under-reporting and under-representation in paediatric vitiligo research, underscoring the need for standardized demographic reporting and more inclusive recruitment strategies.

Clinical and Experimental Dermatology
University of California, Riverside (US), Kaiser Permanente (US), University of Miami (US), Emory University (US), Loma Linda University (US), Coronado Unified School District (US), Ospedale Santa Corona (IT), The University of Texas at Austin (US)
Openalex Percentile: Top 24%
melanin and skin pigmentation
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