Peritoneal Mesonephric-Like Adenocarcinoma Arising in Endometriosis: Case Report and Review of the Literature Expanding the Spectrum of Extrauterine Mesonephric-Like Adenocarcinomas
p.G12V activating mutation.DiscussionMLA has a broad differential diagnosis and is often misinterpreted as other neoplasms. Accurate diagnosis requires an integrated assessment of morphology, immunophenotype, and molecular profile. The peritoneal location, particularly in association with endometriosis, raises the possibility of a peritoneal origin.ConclusionPeritoneal MLA is exceptionally rare. Pathologists should consider MLA in the differential diagnosis of peritoneal tumors, particularly those arising in the setting of endometriosis, to ensure accurate classification and appropriate clinical management.
Authors
- Steven Blaine Holloway (ORCID: https://orcid.org/0000-0003-3543-3896)
- Elena Lucas (ORCID: https://orcid.org/0000-0002-7930-1089)
- Kareem Elfatairy (ORCID: https://orcid.org/0000-0002-3254-9271)
- Jennifer Crow
- Khaled Sabry Mohamed (ORCID: https://orcid.org/0009-0006-2549-4811)
Institutions
- Mansfield University (US)
- Southwestern Medical Center (US)
- OhioHealth Mansfield Hospital (US)
- Southwestern Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- International Journal of Surgical Pathology
- Published
- 2026-04-16
- DOI
- https://doi.org/10.1177/10668969261437122
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00