No detectable infectious agents in langerhans cell histiocytosis with lung involvement
<title>Extract</title> Langerhans cell histiocytosis (LCH) is a rare neoplastic disease of unknown aetiology driven by various somatic mutations in the mitogen-activated protein kinase (MAPK) pathway [1]. LCH is highly heterogeneous and may affect virtually any organ [2]. Lung involvement is frequently observed in adult LCH patients, almost exclusively in young smokers of both sexes [3].
Authors
- Samia Mourah (ORCID: https://orcid.org/0000-0002-9283-1068)
- Valentine Marie Ferré (ORCID: https://orcid.org/0000-0002-2196-6141)
- Gwenaël Lorillon
- Maud Salmona (ORCID: https://orcid.org/0000-0001-7985-6132)
- Véronique Meignin (ORCID: https://orcid.org/0000-0003-0502-9489)
- Fanélie Jouenne (ORCID: https://orcid.org/0000-0002-6706-7424)
- Abdellatif Tazi (ORCID: https://orcid.org/0000-0003-0788-7444)
- Amira Benattia
- Jérôme Le Goff
Institutions
- Inserm (FR)
- Université Paris Cité (FR)
- Sorbonne Paris Cité (FR)
- Hôpital Saint-Louis (FR)
- Ekaterinburg Research Institute of Viral Infections (RU)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2026-04-16
- DOI
- https://doi.org/10.1183/23120541.01689-2025
- Primary Topic
- Histiocytic Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00