Photoacoustic Fingerprinting for Robust Molecular Imaging
mouse livers, PAF detected lipid accumulation associated with steatosis, and in human arteries, it identified molecular signatures consistent with thrombus and lipid-rich plaque. These results establish PAF as a generalizable framework for label-free molecular imaging and a promising step toward quantitative photoacoustic diagnostics.
Authors
- Soon‐Woo Cho (ORCID: https://orcid.org/0000-0002-5019-1429)
- Van Tu Nguyen (ORCID: https://orcid.org/0000-0002-4913-438X)
- Colton McGarraugh
- Rui Yao (ORCID: https://orcid.org/0009-0000-3710-7387)
- Dora Eng-Wu
- Samuel Francis
- Junjie Yao
- Luca Menozzi
Institutions
- Duke University (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-04-15
- DOI
- https://doi.org/10.64898/2026.04.13.718141
- Primary Topic
- Photoacoustic and Ultrasonic Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American Heart Association
- North Carolina Biotechnology Center
- Duke University