Microfluidic analysis of epigallocatechin gallate selectively inhibiting shear-induced platelet aggregation under pathological high shear stress
). By targeting the vWF-GPIbα axis without affecting coagulation, EGCG emerges as a promising prototype for developing novel, bleeding-risk-free antiplatelet therapies.
Authors
- Jia Tang (ORCID: https://orcid.org/0000-0001-7345-3738)
- Zhongyan Gao
- Xuanrong Huan (ORCID: https://orcid.org/0009-0006-6056-1784)
- Jiyu Ran
- Yuan Li (ORCID: https://orcid.org/0000-0002-1202-796X)
- Xuemei Gao (ORCID: https://orcid.org/0000-0002-7572-3997)
- Qirui Cai
- Jie Chen
- Yongbin Hou
- Huijian Liu
- Fangyu Zhou (ORCID: https://orcid.org/0009-0005-8626-8618)
- Suting Zhang
- Anya Dai (ORCID: https://orcid.org/0009-0003-3797-1302)
Institutions
- People's Hospital of Bishan District (CN)
- First People's Hospital of Chongqing (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Clinical Hemorheology and Microcirculation
- Published
- 2026-04-16
- DOI
- https://doi.org/10.1177/13860291261441035
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00