Incremental Value of Adding S100B to NSE for High-Specificity Rule-in of Poor Neurological Outcome After Out-of-Hospital Cardiac Arrest

: Adding S100B to NSE did not improve overall discrimination. The higher 48 h rule-in yield was estimated imprecisely and should be interpreted cautiously. Our findings require external validation before they can be translated to clinical settings.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-04-16
DOI
https://doi.org/10.3390/jcm15083043
Primary Topic
Cardiac Arrest and Resuscitation
Type
article
Field-Weighted Citation Impact
0.00

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article

Incremental Value of Adding S100B to NSE for High-Specificity Rule-in of Poor Neurological Outcome After Out-of-Hospital Cardiac Arrest

Byung Kook Lee, Seokjae Hong, Seungho Lee, Jung Soo Park et al.
Journal of Clinical Medicine
Cardiac Arrest and Resuscitation
article

Incremental Value of Adding S100B to NSE for High-Specificity Rule-in of Poor Neurological Outcome After Out-of-Hospital Cardiac Arrest

Byung Kook Lee, Seokjae Hong, Seungho Lee, Jung Soo Park, Jin Hong Min, Changshin Kang
article en

Abstract

: Adding S100B to NSE did not improve overall discrimination. The higher 48 h rule-in yield was estimated imprecisely and should be interpreted cautiously. Our findings require external validation before they can be translated to clinical settings.

Journal of Clinical MedicineVol. 15(8)
Chungnam National University (KR), Chonnam National University Hospital (KR), Chungnam National University Hospital (KR)
Chungnam National University, National Research Foundation of Korea
Openalex Percentile: Top 19%
Cardiac Arrest and Resuscitation
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