The Tumour Immune Microenvironment as a Predictor of the Response to Neoadjuvant Therapy in Rectal Cancer
: CD8+ TILs have the potential to serve as predictive biomarkers of therapeutic response to neoadjuvant treatment in patients with rectal cancer. Inconsistent findings with FOXP3+ Tregs and CD163+ macrophages reinforce the need for their further investigation.
Authors
- Eleanor J. Cheadle
- Sreya Wadud
- Paul A. Sutton
Institutions
- Manchester Academic Health Science Centre (GB)
- The Christie NHS Foundation Trust (GB)
Publication Details
- Journal
- Cancers
- Published
- 2026-04-16
- DOI
- https://doi.org/10.3390/cancers18081261
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research