Minimally Invasive Therapeutic Drug Monitoring of Immunosuppressants in Children with Kidney Diseases: Validation of Fingerstick Sampling Using LC-MS/MS
: Fingerstick-based microvolume sampling combined with LC-MS/MS provides analytically reliable immunosuppressant quantification in pediatric patients. Although larger clinical validation is required, this minimally invasive approach may reduce procedural burden and may support future outpatient or home-based TDM strategies.
Authors
- Hitoshi Osaka (ORCID: https://orcid.org/0000-0002-1320-1165)
- Mitsuaki Yoshino
- Tomomi Maru
- Masanori Kurosaki (ORCID: https://orcid.org/0000-0003-4447-7786)
- Natsuka Kimura
- Jun Aoyagi (ORCID: https://orcid.org/0000-0001-6899-6797)
- Takahiro Kanai
- Takane Ito
- Marika Ishii (ORCID: https://orcid.org/0009-0004-7335-7286)
- Kenichi Aizawa
- Ryozo Nagai
- Kazuya Tanimoto
Institutions
- Jichi Medical University (JP)
Publication Details
- Journal
- Pharmaceuticals
- Published
- 2026-04-16
- DOI
- https://doi.org/10.3390/ph19040630
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00