Use of Imaging to Guide Eligibility for Reperfusion Therapies in Acute Ischemic Stroke
Imaging is pivotal across all stages of stroke care, particularly acutely where it is central to diagnosis, prognostication, and selecting patients with a favorable benefit-to-risk profile for thrombolysis and endovascular therapy. With new therapies emerging and treatment eligibility expanding to broader patient populations, imaging strategies have evolved. This review will highlight the evolution in acute stroke imaging, examine emerging and ongoing clinical trials in which imaging is integral to patient selection, and identify priority areas for future research and development.
Authors
- Vignan Yogendrakumar (ORCID: https://orcid.org/0000-0001-8814-6853)
- Shelagh B. Coutts (ORCID: https://orcid.org/0000-0001-5090-5105)
- Yunyun Xiong (ORCID: https://orcid.org/0000-0003-1353-2295)
- Mohamad K. Abdalkader (ORCID: https://orcid.org/0000-0002-9528-301X)
- Bruce C.V. Campbell (ORCID: https://orcid.org/0000-0003-3632-9433)
- Mark William Parsons (ORCID: https://orcid.org/0000-0001-8874-2487)
- Götz Thomalla (ORCID: https://orcid.org/0000-0002-4785-1449)
- Thanh N. Nguyen (ORCID: https://orcid.org/0000-0002-2810-1685)
Institutions
- Boston Medical Center (US)
- Allen Institute for Brain Science (US)
- The Royal Melbourne Hospital (AU)
- Universität Hamburg (DE)
- Ottawa Hospital (CA)
- Beijing Tian Tan Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- University Medical Center Hamburg-Eppendorf (DE)
- Klinik und Poliklinik für Neurologie (DE)
- Ontario Brain Institute (CA)
- University of Newcastle Australia (AU)
Publication Details
- Journal
- Stroke
- Published
- 2026-04-16
- DOI
- https://doi.org/10.1161/strokeaha.125.052748
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00