Unusual Case of Neuromeningeal Late Relapse of POLE Mutated Endometrioid Carcinoma: A Case Report and Systematic Review

: While POLE-mutated tumors overall retain an excellent prognosis, rare cases may follow an atypical and aggressive course. Improved molecular annotation and integrated risk-stratification models are needed to better identify this minority of higher-risk patients.

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Publication Details

Journal
Current Oncology
Published
2026-04-16
DOI
https://doi.org/10.3390/curroncol33040219
Primary Topic
Endometrial and Cervical Cancer Treatments
Type
article
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article

Unusual Case of Neuromeningeal Late Relapse of POLE Mutated Endometrioid Carcinoma: A Case Report and Systematic Review

Alexis Marguerit, Stéphanie Nougaret, Pierre‐Emmanuel Colombo, Stanislas Quesada et al.
Current Oncology
Endometrial and Cervical Cancer Treatments
article

Unusual Case of Neuromeningeal Late Relapse of POLE Mutated Endometrioid Carcinoma: A Case Report and Systematic Review

Alexis Marguerit, Stéphanie Nougaret, Pierre‐Emmanuel Colombo, Stanislas Quesada, Cristina Leaha, Michel Fabbro, Emma Donati, Noémie Drappier
article en

Abstract

: While POLE-mutated tumors overall retain an excellent prognosis, rare cases may follow an atypical and aggressive course. Improved molecular annotation and integrated risk-stratification models are needed to better identify this minority of higher-risk patients.

Current OncologyVol. 33(4)
Institut de Recherche en Cancérologie de Montpellier (FR), Eau de Paris (France) (FR)
Good health and well-being
Openalex Percentile: Top 22%
Endometrial and Cervical Cancer Treatments
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