The Impact of Malnutrition and Multimodal Prehabilitation on Quality of Life in Head and Neck Cancer Patients Following Resection and Microvascular Reconstruction: A Cross-Sectional Study
Our findings suggest that malnutrition is a potential risk factor for adverse outcomes in curative HNSCC therapy. The GMS is a sensitive tool for identifying patients at risk of malnutrition in HNSCC surgery prehabilitation. Our multimodal protocol was associated with improved postoperative outcomes following curative surgical resection and free flap reconstruction. The observed associations may reflect potential synergistic interactions within the multimodal framework.
Authors
- Gian Battista Bottini (ORCID: https://orcid.org/0000-0002-4116-6264)
- Florian Huber (ORCID: https://orcid.org/0000-0002-2896-7921)
- Benjamin Walch (ORCID: https://orcid.org/0000-0002-6300-9390)
- Katharina Zeman-Kuhnert (ORCID: https://orcid.org/0000-0002-2569-6898)
- Alexander Gaggl (ORCID: https://orcid.org/0009-0000-7634-0085)
- Birgit Mitter (ORCID: https://orcid.org/0000-0003-3170-1080)
- Martin Geroldinger (ORCID: https://orcid.org/0000-0002-7858-323X)
- Anna Lena Bridts
- Valentina Ranstl
Institutions
- Paracelsus Medical University (AT)
Publication Details
- Journal
- Journal of Clinical Medicine
- Published
- 2026-04-16
- DOI
- https://doi.org/10.3390/jcm15083050
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00