Peanut Oral Immunotherapy in Children: An Italian Single-Center Retrospective Cohort Study
In this real-world single-center cohort, P-OIT using toasted peanuts was feasible in a subset of patients and was associated predominantly with mild adverse reactions, although systemic reactions were also recorded. Treatment discontinuation and adherence remain relevant challenges. These findings highlight the need for prospective, controlled studies to better define the role, safety profile, and patient selection criteria for food-based P-OIT protocols in settings where standardized products are not available.
Authors
- Mattia Giovannini (ORCID: https://orcid.org/0000-0001-9568-6882)
- Francesca Mori (ORCID: https://orcid.org/0000-0001-7483-0128)
- Claudia Valleriani (ORCID: https://orcid.org/0000-0002-2071-1745)
- Giulia Liccioli (ORCID: https://orcid.org/0000-0002-5216-0423)
- Erika Paladini (ORCID: https://orcid.org/0000-0001-7116-0325)
- Simona Barni (ORCID: https://orcid.org/0000-0001-5598-2740)
- Benedetta Pessina (ORCID: https://orcid.org/0000-0002-1387-3463)
- Julia Upton (ORCID: https://orcid.org/0000-0001-5320-4232)
- Leonardo Tomei (ORCID: https://orcid.org/0000-0002-7177-7939)
- Lucrezia Sarti (ORCID: https://orcid.org/0000-0001-8055-3788)
- Francesco Catamerò (ORCID: https://orcid.org/0009-0001-5633-9025)
- Camilla Sertori (ORCID: https://orcid.org/0009-0006-5733-4193)
Institutions
- University of Siena (IT)
- University of Toronto (CA)
- Hospital for Sick Children (CA)
- Meyer Children's Hospital (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Florence (IT)
Publication Details
- Journal
- Nutrients
- Published
- 2026-04-16
- DOI
- https://doi.org/10.3390/nu18081252
- Primary Topic
- Food Allergy and Anaphylaxis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Regione Toscana