Integrated Network Pharmacology, Molecular Docking and Experimental Validation Reveal That Quercetin Suppresses Clear Cell Renal Cell Carcinoma via MMP9-Associated Macrophage Polarization
, particularly its active component quercetin, may inhibit ccRCC progression via inhibiting MMP9-mediated M2 macrophage polarization.
Authors
- Jianping Wu (ORCID: https://orcid.org/0000-0002-9363-3848)
- Chengyun Xu (ORCID: https://orcid.org/0000-0003-3747-3728)
- J Q Huang
- Dapeng Wang (ORCID: https://orcid.org/0000-0001-5213-4949)
Institutions
- Nanchang University (CN)
- Ruijin Hospital (CN)
- Second Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Biomedicines
- Published
- 2026-04-16
- DOI
- https://doi.org/10.3390/biomedicines14040904
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00