Association Between Maternal Gestational Diabetes, Cord Blood DNA Methylation, and Offspring Neurodevelopment
highlight a systemic metabolic 'cross-talk' influencing neurodevelopment. Although these pilot findings are hypothesis-generating and require further functional validation, this study provides pioneering evidence that neurodevelopmental alterations in the offspring of mothers with GDM are potentially associated with intrauterine epigenetic modifications detectable at birth.
Authors
- C Flores
- E. Padrón-Pérez
- Adrián Muñoz-Barrera
- Laura Tascón-Padrón
- Olivia Orribo-Morales
- Rafaela González-Montelongo
- Nieves Luisa González-González
- José Ramón Castro-Conde
- Enrique González-Dávila
- José Miguel Lorenzo-Salazar
- Marina Armas-González
- Candelaria González-Campo
Institutions
- Universidad de La Laguna (ES)
- University Hospital Bonn (DE)
- Hospital Universitario de Canarias (ES)
- Instituto de Salud Carlos III (ES)
- Hospital General Universitario Gregorio Marañón (ES)
- Hospital Universitario Nuestra Señora de Candelaria (ES)
- Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES)
- Instituto Tecnológico y de Energías Renovables (ES)
Publication Details
- Journal
- International Journal of Molecular Sciences
- Published
- 2026-04-16
- DOI
- https://doi.org/10.3390/ijms27083571
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Instituto Tecnológico y de Energías Renovables
- Ministerio de Ciencia e Innovación
- Instituto de Salud Carlos III