Structure-Driven Bioactivity of Chitosan-Agarose-Gelatin Hydrogels Functionalized with Tannic Acid-Cu <sup>2+</sup> /Sr <sup>2+</sup> Complexes
for its reported osteoconductive potential, no osteogenic stimulation was observed under the tested conditions. This finding indicates that further optimization of ion ratios and/or TA concentration is required to achieve clinically relevant multibiofunctional hydrogels for bone-related applications.
Authors
- Diego Mantovani (ORCID: https://orcid.org/0000-0001-9672-895X)
- Elliott Cournoyer
- Vanessa P. Houde (ORCID: https://orcid.org/0000-0003-1932-805X)
- Marcin Wekwejt (ORCID: https://orcid.org/0000-0002-6889-7825)
- Silvia Rodríguez-Fernández
- Florence Desgagne
- Pascale Chevallier
Institutions
- Gdańsk University of Technology (PL)
- Shiraz University of Technology (IR)
- Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (ES)
- Université Laval (CA)
Publication Details
- Journal
- ACS Applied Materials & Interfaces
- Published
- 2026-04-16
- DOI
- https://doi.org/10.1021/acsami.6c01091
- Primary Topic
- Hydrogels: synthesis, properties, applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Canada Research Chairs
- Narodowa Agencja Wymiany Akademickiej
- Natural Sciences and Engineering Research Council of Canada
- PRIMA Québec