IgG N-Glycosylation During Atorvastatin Therapy After Acute Coronary Syndrome is Associated with LDL Cholesterol Reduction

: Specific glycan traits are associated with the degree of LDL-C reduction achieved during statin therapy, particularly in patients with high baseline LDL-C. These findings suggest that IgG glycosylation patterns may reflect biological phenotypes associated with differential lipid-lowering responsiveness after ACS.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-04-16
DOI
https://doi.org/10.3390/jcm15083056
Primary Topic
Glycosylation and Glycoproteins Research
Type
article
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article

IgG N-Glycosylation During Atorvastatin Therapy After Acute Coronary Syndrome is Associated with LDL Cholesterol Reduction

Domagoj Mišković, Ivana Jurin, Irzal Hadžibegović, Barbara Radovani et al.
Journal of Clinical Medicine
Glycosylation and Glycoproteins Research
article

IgG N-Glycosylation During Atorvastatin Therapy After Acute Coronary Syndrome is Associated with LDL Cholesterol Reduction

Domagoj Mišković, Ivana Jurin, Irzal Hadžibegović, Barbara Radovani, Nikol Mraz, G Lauc, Ana Đanić Hadžibegović, Ivan Gudelj
article en

Abstract

: Specific glycan traits are associated with the degree of LDL-C reduction achieved during statin therapy, particularly in patients with high baseline LDL-C. These findings suggest that IgG glycosylation patterns may reflect biological phenotypes associated with differential lipid-lowering responsiveness after ACS.

Journal of Clinical MedicineVol. 15(8)
University Hospital Centre Zagreb (HR), University of Zagreb (HR), University Hospital Dubrava (HR), Genos (Croatia) (HR), University of Slavonski Brod (HR), Science Research Laboratory (US), University of Osijek (HR)
Good health and well-being
Openalex Percentile: Top 21%
Glycosylation and Glycoproteins Research
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IgG N-Glycosylation During Atorvastatin Therapy After Acute Coronary Syndrome is Associated with LDL Cholesterol Reduction — Domagoj Mišković, Ivana Jurin, et al. · Journal of Clinical Medicine (2026) | TGRS Research Map | TGRS