TRPV4 mediates macrophage polarization involved in inflammatory root resorption induced by mechanical pressure
influx and upregulates the M1/M2 macrophage polarization ratio. In conclusion, our findings indicate that TRPV4 serves as a critical mediator in mechanical pressure-regulated macrophage polarization during OIIRR.
Authors
- Lizhiyi Liu
- Xuanchen Su
- Wenjun Cai (ORCID: https://orcid.org/0009-0006-2284-2964)
- Min Jin (ORCID: https://orcid.org/0009-0005-1653-6867)
- Meng Wang (ORCID: https://orcid.org/0009-0003-6475-176X)
Institutions
- Yunnan University (CN)
- Kunming Medical University (CN)
- Stomatology Hospital (CN)
Publication Details
- Journal
- Channels
- Published
- 2026-04-16
- DOI
- https://doi.org/10.1080/19336950.2026.2660014
- Primary Topic
- Ion Channels and Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Kunming Medical University
- Yunnan Provincial Science and Technology Department