Clinical application of ozone hydrotherapy combined with scalp complex acid treatment for moderate to severe scalp seborrheic dermatitis
Introduction: This study evaluates the effectiveness of combining ozone hydrotherapy with scalp complex acid in treating scalp seborrheic dermatitis (SSD). Methods: A total of 96 patients with moderate to severe SSD were randomly assigned to either the Control group (treated with scalp complex acid) or the Observation group (treated with a combination of ozone hydrotherapy and scalp complex acid). The treatment period lasted 4 weeks. SSD severity was evaluated using a 16-point composite score that assessed erythema, scaling, and pruritus. Total skin damage score was rated on a 4-point scale. Scalp sebum levels were measured using a Sebumeter SM 810, and serum levels of IL-1β and TNF-α were quantified using enzyme-linked immunosorbent assay. Results: < 0.001). Discussion: The combination of ozone hydrotherapy and scalp complex acid showed enhanced therapeutic benefits for SSD, leading to improved clinical outcomes and a reduction in systemic inflammation.
Authors
- Sui Liu
- Jun Chen (ORCID: https://orcid.org/0000-0002-4059-3512)
- Qianqian Xu
- Yiying Ma
- Xiaoxia Shi
- Fangling Wang
Institutions
- Suizhou Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-04-16
- DOI
- https://doi.org/10.3389/fmed.2026.1791653
- Primary Topic
- Medical and Biological Ozone Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00