Age-associated increases in inter-individual gene expression variability across human tissues

, for RT-qPCR experiments in studying age-related gene expression changes in humans. Together, our findings suggest that aging involves both coordinated transcriptional programs and increased stochasticity across individuals and cells.

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Publication Details

Journal
bioRxiv (Cold Spring Harbor Laboratory)
Published
2026-04-16
DOI
https://doi.org/10.64898/2026.04.14.718522
Primary Topic
Gene expression and cancer classification
Type
article
Field-Weighted Citation Impact
0.00
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article

Age-associated increases in inter-individual gene expression variability across human tissues

Xiao Ping Dong, Laura J. Niedernhofer, Josh Bartz, Lei Zhang et al.
bioRxiv (Cold Spring Harbor Laboratory)
Gene expression and cancer classification
article

Age-associated increases in inter-individual gene expression variability across human tissues

Xiao Ping Dong, Laura J. Niedernhofer, Josh Bartz, Lei Zhang, Paola Rivera
article en

Abstract

, for RT-qPCR experiments in studying age-related gene expression changes in humans. Together, our findings suggest that aging involves both coordinated transcriptional programs and increased stochasticity across individuals and cells.

bioRxiv (Cold Spring Harbor Laboratory)
University of Minnesota (US), Twin Cities Orthopedics (US)
Openalex Percentile: Top 26%
Gene expression and cancer classification
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