Interpreting circulating microbiome-related metabolites in coronary heart disease

Circulating microbiome-related metabolites have emerged as promising biomarkers for coronary heart disease. A recent multi-stage study in PLOS Medicine strengthens signal prioritization but highlights the persistent gap between association and causality.

Authors

Zhonghan Sun
Yan Zheng (ORCID: https://orcid.org/0000-0003-1129-3147)
Mengkun Shi

Institutions

Fudan University (CN)
Huashan Hospital (CN)

Publication Details

Journal: PLoS Medicine
Published: 2026-04-15
DOI: https://doi.org/10.1371/journal.pmed.1005056
Primary Topic: Gut microbiota and health
Type: article
Field-Weighted Citation Impact: 0.00

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article

Interpreting circulating microbiome-related metabolites in coronary heart disease

Zhonghan Sun, Yan Zheng, Mengkun Shi

Apr 15, 2026

PLoS Medicine

Gut microbiota and health

article

Interpreting circulating microbiome-related metabolites in coronary heart disease

Zhonghan Sun, Yan Zheng, Mengkun Shi

April 15, 2026article en

Abstract

PLoS MedicineVol. 23(4)

Fudan University (CN), Huashan Hospital (CN)

Good health and well-being

Openalex Percentile: Top 22%

Gut microbiota and health

DOI Open Access PDF OpenAlex

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Interpreting circulating microbiome-related metabolites in coronary heart disease — Zhonghan Sun, Yan Zheng, et al. · PLoS Medicine (2026) | TGRS Research Map | TGRS